Towards Personalized Neuromodulation

Simultaneous HD tES & HD EEG

As one of the most exciting advances in the field of brain research, there is a surge of interest in combining HD EEG with multi-channel transcranial electrical stimulation for non-invasive neuromodulation. Experimentally, this technique is used to modulate the plasticity of the brain to understand the brain connectivity, network dynamics, and the effects on cognitive performance.

Powerful yet easy to use, the Quest HD+Stim provides an elegant solution for your neuromodulation research. Extensive software APIs and robust on-board processing give you the freedom to experiment with novel waveforms and modulate experimental stimuli based on your subject’s behavioral and/or electrophysiological responses.

The Quest HD+Stim neurostimulation system can target specific cortical regions for stimulation and simultaneously record up to 256 channels of EEG while utilizing the same hardware, electrode caps, and software platform.

neuromodulator eeg cap
neurostimulation system


  • Flexible stimulation – Unlike many commercially available products, the Quest HD+Stim is not limited to simple waveforms. Stimulation parameters can be updated every 33us, making truly arbitrary waveforms possible.
  • Real-time, closed-loop control – Low latency, custom stimulation paradigms can be programmed with unique triggers and controlled in real-time with comprehensive MATLAB and Python APIs.
  • Multi-modal – Record HD EEG & stimulate with HD tES in a single hardware and software platform. Easily synchronize analog and digital inputs and outputs from external devices with neural data.
  • Programmable montage – Enables advanced investigations with the flexibility to select multiple anodal/cathodal pairs simultaneously and change locations over time.

Active Front Ends

Neuromed’s unique active Front End design results in unparalleled signal fidelity – a key requirement for many single trial BCI applications.


Real-time, closed-loop control

Well documented MATLAB and Python APIs for real-time feedback and control. Custom stimulation paradigms can be programmed and initiated with unique and varied triggers.


Wearable system

At merely 700 grams, the Quest provides a light weight and portable form factor, only enhanced by internal battery and Wifi capabilities. The Quest can be belt worn or placed in a backpack for optimal experimental freedom.

One of the most exciting advances in the field of brain research is non-invasive neuromodulation. In particular, there is an increasing amount of interest in combining HD EEG with multi-channel transcranial electrical stimulation to understand the underlying brain connectivity and cognitive performance.

The Quest HD+Stim provides a powerful yet elegant and easy to use platform for your stimulation research supported by a full complement of software, including the Compass software, APIs and third-party software.

The Quest HD+Stim amplifiers can deliver selectable transcranial electrical stimulation and provides full spectrum of stimulation, as well as concurrent recording abilities. This simultaneous stimulation and recording is the ideal tool to help understand the impact and effect of TES.

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