Single unit-derived connectivity networks in tuberous sclerosis complex reveal propensity for network hypersynchrony driven by tuber-tuber interactions (opens in a new tab)
Scientific Reports, 14(1): 31654. doi:10.1038/s41598-024-80634-5
Applications
Research in the Hospital
BCI & Prosthetic DevelopmentWe record from and stimulate both the peripheral and central nervous systems in both primates and humans. Ripple’s ecosystem allows us to easily interface with all these systems with minimal development. This allows us to spend more time on the science and less on getting experiments working.
Charles Greenspon University of Chicago · Sensory Neurophysiology Epilepsy Monitoring Unit Research
Ripple records and stimulates in parallel with the clinical system, from the same depth electrodes, without interrupting clinical care.
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Parallel macro recording and stimulation
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Microelectrodes from depth electrodes
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Flexible, closed-loop stimulation
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Works with your clinical system
Research in parallel with clinical monitoring
Clinical adapters connect the Summit in parallel with the clinical EEG system, so research recording and stimulation run on the macro contacts while clinical monitoring continues. Microwires on micro-macro depth electrodes connect to Ripple front ends for single-unit and high-frequency recording.
Hardware configuration
- Explorer Summit Research recording and stimulation
- Clinical adapters with macro front ends Macro or Macro2+stim front ends, in parallel with the clinical system on the macro contacts
- Microelectrode front ends Micro2 or Micro3 (or the +stim versions): record and stimulate on microelectrodes, connected directly in the headwrap
- Analog + Digital I/O Synchronize with clinical and behavioral events
More publications
Interacting ventral temporal gradients of timescales and functional connectivity and their relationships to visual behavior (opens in a new tab)
iScience, 27(6): 110003. doi:10.1016/j.isci.2024.110003
Ripple hardware for Epilepsy Monitoring Unit Research
Intraoperative Monitoring Research
Run research in the operating room alongside the existing intraoperative monitoring equipment, without disrupting the clinical workflow.
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Connects in parallel
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Clinical workflow preserved
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Same channels, minimal noise
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Quick connect and disconnect
Research alongside clinical monitoring
A clinical adapter connects the Summit in parallel with the clinical monitoring system, giving researchers access to the same electrode channels while the clinical setup and workflow stay unchanged.
- Explorer Summit Research recording and stimulation
- Clinical adapter Splits the macro channels between the clinical system and Ripple
- Clinical monitoring system Unchanged clinical setup
- Micro interface Records from microelectrodes, connected at the patient’s head
Ripple hardware for Intraoperative Monitoring Research
Planning a study?
Our team can help you configure the right Explorer Summit system for your research.