NOMAD

Invasive & Multi-Modal Neurophysiology System

The Explorer Nomad

Multi-modal powerful electrophysiology in a lightweight and portable package

Ripple Neuromed’s Nomad processor provides up to 512 channels of simultaneous recording and stimulation that can fit in the palm of your hand.

A truly modular system, the Nomad can record multi-modal electrophysiological signals of uncompromising quality with specialized Front Ends. On-board processing and advanced APIs provides the flexibility for any application. Easily setup in minutes, the Nomad can quickly transition between the laboratory and the operating room.

With game-changing versatility, the Nomad processor can be used in the lab and the operating room as a stand-alone system or to complement existing clinical systems in the epilepsy monitoring unit. Compatible with both high impedance microelectrodes and standard clinical electrodes, you can record a full range of physiological data with one processor.

With wireless data transmission, integrated battery, and internal data storage, the Nomad processor is a portable platform for advanced neurophysiology, neuromodulation, neuroprosthesis development, and brain machine interface experiments.

Highlights

  • Up to 512 channels of simultaneous stimulation and recording
  • Specialized Front Ends to optimize electrophysiological recordings
  • Onboard processing for dynamic experiments and closed-loop stimulation
  • Advanced API for custom applications
  • Small and portable for mobile applications
  • Meets safety standards for laboratory and clinical research

Up to 512 channels

of recording per device (1024 total)

Record and Stimulate

simultaneously on all channels

30 kHz sampling rate

for single-unit recordings

Portable – 700 grams. Easily transport between hospitals or laboratories.

Versatile – dedicated front ends. simultaneous stimulation and recording for any experiment.

Wearable – wireless communications. integrated battery. on-board storage. pack it up and go.

Seamless Setup – set up and begin recording in minutes.

REAL-TIME, CLOSED-LOOP CONTROL – PROGRAMMATIC CONTROL. REAL-TIME FEEDBACK. MATLAB & PYTHON APIs

PORTABILITY

At merely 700 grams, the Nomad provides a light weight and portable form factor that can easily be transported between hospitals or laboratories

SAFETY

Already used around the world and reported in high-impact, peer-reviewed journals, the Nomad is designed to meet ISO 60601 safety standards for laboratory and clinical research

Quest HD

Turn-Key Mobile EEG and ERP

Small and lightweight, the Quest HD frees your subjects to move freely and engage in natural behavior. Capable of true high density recording with a max channel count of up to 512 channels, with 24-bit resolution and sampling rate of 7.k ksps for the highest quality data.

Integrating with the Explorer line’s Compass software allows for turn-key setup with automatic device and accessory recognition, and an array of useful features including real-time impedance measurement, integrated video tracking through multiple USB cameras, and graphical control of ERP triggers and configuration.

The Quest HD elimates the need for cables, featuring wireless data transmission, an integrated battery, and internal data storage. With on-board processing, and a bevy of inputs and outputs, and a powerful yet user-friendly API, the Quest HD can be custom programmed for your unique paradigms with real-time control of external devices, stimulators and trackers. In addition to EEG and ERPs, the Quest is also compatible with the Explorer EMG front end for concurrent bipolar EMG recordings.

Highlights

  • A completely wearable EEG/ERP solution, with wireless communication and on-board data storage
  • On-board processing and an easy-to-use API for custom applications
  • Meets safety standards for laboratory and clinical research

Specifications

Quest HD Processor

Number of Channels up to 512
Analog I/O up to 28 inputs and 28 outputs
Digital I/O up to 20 input and 20 outputs, plus 2 strobes
Battery Life Internal, up to 2 hours; External, 4 – 6 hours
Data Communication with PC Gigabit Ethernet or Wi-Fi
Dimensions 183 mm x 95 mm x 36 mm
Weight 700 g

Recording

Resolution 24-bit
Inferred Noise <1 μVrms
Common Mode Rejection Ratio -110dB
Input Range Min ± 0.1875 V at a gain of 24
Input Range Max ± 2 V at a gain of 1
Input Impedance 1 GΩ, 20 pF

Quest HD+Stim

Concurrent Transcranial Stimulation and Electroencephalography

Adding to the mobility and features of the Quest HD, the Quest HD+Stim add the ability to do concurrent tCS along with your EEG and ERP recordings.

Powerful on-board processing allows for generation of complex waveforms, allowing you to use common tCS modalities (such as tDCS, tACS, tPCS or tRCS) or experiment with novel waveforms, even modulating or creating stimuli based on the subject’s behavioral or electrophysiological responses. Stimulation can be applied to any of the recording channels, with a switch time of less than a millisecond.

Highlights

  • Concurrent tCS and EEG/ERP
  • Selectable stimulation channels (switch time < 1ms)
  • Closed-loop control of tCS parameters
  • All of the mobility and features of the Quest HD
  • Meets safety standards for laboratory and clinical research

Specifications

Quest HD Processor

Number of Channels up to 512
Analog I/O up to 28 inputs and 28 outputs
Digital I/O up to 20 input and 20 outputs, plus 2 strobes
Battery Life Internal, up to 2 hours; External, 4 – 6 hours
Data Communication with PC Gigabit Ethernet or Wi-Fi
Dimensions 183 mm x 95 mm x 36 mm
Weight 700 g

Recording

Resolution 24-bit
Inferred Noise <1 μVrms
Common Mode Rejection Ratio -115dB
Input Range Min ± 0.1875 V at a gain of 24
Input Range Max ± 2 V at a gain of 1
Input Impedance 300 MΩ, 150 pF

Stimulation

Current Range 100 μA – 15 mA
Compliance Voltage ± 9 V to ± 30 V (configurable)
Pulse Width Min 33μs
Bandwidth DC to 120kHz

The EEG family of front ends were designed for noninvasive surface electrodes. As the name implies, it is designed with EEG specifically in mind, however it is suitable for any surface recordings that do not require bipolar or true differential referencing (for these applications the Physio16 is recommended). The stimulation version, the EEG+tES, is designed for stimulation from surface electrodes, such as transcranial stimulation (tCS), or transcutaneous nerve or spinal stimulation (TENS, TSS).

EEG and EEG+tES

Features

  • Compatible with any passive EEG cap
  • Small, multichannel amplifier combines the signal quality of active caps with the ease-of-use and robustness of passive caps
  • Combined with the Quest HD, is ideal for Mobile EEG/ERP
ripple-eeg-view-5-explorer2

Primary Use Cases

  • EEG
  • ERP
  • tCS
  • TENS
  • TSS

Specifications

EEG
Compatible Processors Nomad or any Quest HD
Channels 32 or 128, single reference
Bit Depth 24-bit
Resolution 0.022 μV/bit
Sample Rate 7.5 ksps
Bandwidth DC to 2kHz
CMMR 110 dB
Inferred Noise <1 µVrms at 7.5 ksps
Input Range Min ± 0.1875 V at a gain of 24
Input Range Max ± 2 V at a gain of 1
Input Impedance 1 Gohm, 20 pF
EEG+tES
Compatible Processors Nomad or Quest HD+stim
Channels 32 or 128, single reference
Bit Depth 24-bit
Resolution 0.022 μV/bit
Sample Rate 7.5 ksps
Bandwidth DC to 2kHz
CMMR 110 dB
Inferred Noise <1 µVrms at 7.5 ksps
Input Range Min ± 0.1875 V at a gain of 24
Input Range Max ± 2 V at a gain of 1
Input Impedance 1 Gohm, 20 pF
Stimulation Waveforms tDCS, tRNS, tACS, tPCS, user defined
Stimulation Current Range ±15 mA
Compliance Voltage ±9 to 30V (configurable)
Min Pulse Width 33 µs
Stimulation Frequency up to 15kHz

The Explorer line offers two families of front ends for invasive recordings, the Micro2 and the Macro. The Micro2 was designed with high-impedance, micro electrodes in mind. Capable of recording single units, it has a sampling rate of up to 30 ksps. The Micro2+stim is capable of stimulating on all channels simultaneously, making it ideal for all manner of research applications. To avoid delivering excess power to high-impedance electrodes, the Micro2+stim has a lower maximum per channel current compared to the macro

The Macro was designed for standard clinical electrodes. Compared to the Micro2, it has a more focused bandwidth to optimize it for applications such as high-resolution ECoG or sEEG. The Macro2+Stim maximum stimulation current is higher to match common clinical stimulators, while limiting current flow to one anode and one cathode per 16 channel bank to prevent excessive discharge. However, due to the fast switching times common to all Ripple Neuromed stimulating front ends, all channels can be effectively stimulated at once by using interleaved pulse trains.

Macro and Macro+stim Front Ends

Features

  • Compatible with macro and microelectrodes
  • 1.5mm touchproof connector interface
  • Constant current and constant voltage output modes
  • One selectable stimulation channel (switch time < 1ms)
  • Monopolar or bipolar waveforms
  • Programmatic control of waveforms and train parameters
ecogstim-explorer-green2

Primary Use Cases

  • ECoG
  • sEEG
  • LFPs
  • DBS
  • Closed-Loop Stimulation

Specifications

Macro
Compatible Processors Nomad
Channels 32 or 128, single reference
Bit Depth 24-bit
Resolution 0.022 μV/bit
Sample Rate 7.5 ksps
Bandwidth DC to 2kHz
CMMR 110 dB
Inferred Noise <1 µVrms at 7.5 ksps
Input Range Min ± 0.1875 V at a gain of 24
Input Range Max ± 2 V at a gain of 1
Input Impedance 1 Gohm, 20 pF
Macro+stim
Compatible Processors Nomad
Channels 32 or 128, single reference
Bit Depth 24-bit
Resolution 0.022 μV/bit
Sample Rate 7.5 ksps
Bandwidth 0.03 Hz to 2kHz
CMMR 110 dB
Inferred Noise <1 µVrms at 7.5 ksps
Input Range Min ± 0.1875 V at a gain of 24
Input Range Max ± 2 V at a gain of 1
Input Impedance 1 Gohm, 150 pF
Stimulation Current Range ±15 mA
Compliance Voltage ±9 to 30V (configurable)
Min Pulse Width 33 µs
Stimulation Frequency up to 15kHz




Micro2 and Micro2+stim Front Ends

Features

Features

  • High resolution, high sampling rate (30 ksps) recording
  • Stimulation on all channels
  • Programmatic control of waveforms and train parameters

Primary Use Cases

  • Single unit/multi-unit activity
  • ECoG
  • LFPs
  • Closed-Loop Stimulation
Micro2
Compatible Processors Nomad
Channels 32, single reference
Bit Depth 24-bit
Resolution 0.125, 0.25, or 0.5 μV/bit
Sample Rate 30 ksps
Bandwidth 0.1 Hz to 2 kHz
CMMR 82 dB
Inferred Noise 2.1 µVrms
Input Range Min ± 4 mV
Input Range Max ± 12 V
Micro2+stim
Compatible Processors Nomad
Channels 32, single reference
Bit Depth 24-bit
Resolution 0.125, 0.25, or 0.5 μV/bit
Sample Rate 30 ksps
Bandwidth 1 Hz to 7.5 kHz
CMMR 82 dB
Inferred Noise 2.1 µVrms
Input Range Min ± 4 mV
Input Range Max ± 12 mV
Stimulation Current Range ±1.5 mA
Compliance Voltage ±8.5V
Min Pulse Width 33 µs
Stimulation Frequency up to 15kHz

The Physio was designed specifically with electromyography in mind, although can be used for any type of electrophysiology from the body, such as ECG or noninvasive peripheral nerve recordings. It comes in both a 32 channel shared reference version, as well as a 16 channel bipolar version. The Physio does not have a stimulating version, but can be used with stimulating front ends for applications that need stimulation, such as electrically evoked potentials.

Physio 16 and Physio 32 Front Ends

Features

  • 16 differential pairs or 32 single-ended channels
  • Designed for bipolar EMG or single-ended HD EMG recordings
  • 52 mm x 36 mm x 4.75 mm
  • 13.5 g
emg

Primary Use Cases

  • EMG
  • MEP
  • Noninvasive Peripheral Nerve recordings

Specifications

Physio16
Compatible Processors Nomad or any Quest HD
Channels 16, true differential referencing
Bit Depth 24-bit
Resolution 0.022 μV/bit
Sample Rate 7.5 ksps
Bandwidth DC to 2kHz
CMMR 110 dB
Inferred Noise <1 µVrms at 7.5 ksps
Input Range Min ± 0.1875 V at a gain of 24
Input Range Max ± 2 V at a gain of 1
Input Impedance 1 Gohm, 20 pF
Physio32
Compatible Processors Nomad or any Quest HD
Channels 32, single reference
Bit Depth 24-bit
Resolution 0.022 μV/bit
Sample Rate 7.5 ksps
Bandwidth DC to 2kHz
CMMR 110 dB
Inferred Noise <1 µVrms at 7.5 ksps
Input Range Min ± 0.1875 V at a gain of 24
Input Range Max ± 2 V at a gain of 1
Input Impedance 1 Gohm, 20 pF

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